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Departments of Psychiatry and Pathology, Dalhousie University, Halifax, B3H 2E2, Nova Scotia, Canada
Список исп. литературыСкрыть список 1. Whiteford HA, Degenhardt L, Rehm J et al. Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010. Lancet 2013;382:1575‐86. 2. Walker ER, McGee RE, Druss BG. Mortality in mental disorders and global disease burden implications: a systematic review and meta‐analysis. JAMA Psychiatry 2015;72:334‐41. 3. Gottesman II, Laursen TM, Bertelsen A et al. Severe mental disorders in offspring with 2 psychiatrically ill parents. Arch Gen Psychiatry 2010;67:252‐7. 4. Rasic D, Hajek T, Alda M et al. Risk of mental illness in offspring of parents with schizophrenia, bipolar disorder, and major depressive disorder: a meta‐analysis of family high‐risk studies. Schizophr Bull 2014;40:28‐38. 5. Polderman TJ, Benyamin B, de Leeuw CA et al. Meta‐analysis of the heritability of human traits based on fifty years of twin studies. Nat Genet 2015;47:702‐9. 6. Gershon ES. Bipolar illness and schizophrenia as oligogenic diseases: implications for the future. Biol Psychiatry 2000;47:240‐4. 7. Crow TJ. A continuum of psychosis, one human gene, and not much else – the case for homogeneity. Schizophr Res 1995;17:135‐45. 8. Schizophrenia Working Group of the Psychiatric Genomics Consortium. Biological insights from 108 schizophrenia‐associated genetic loci. Nature 2014;511:421‐7. 9. Hyde CL, Nagle MW, Tian C et al. Identification of 15 genetic loci associated with risk of major depression in individuals of European descent. Nat Genet 2016;48:1031‐6. 10. Psychiatric Genomics Consortium . Large‐scale genome‐wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Nat Genet 2011;43:977‐83. 11. Robinson EB, St Pourcain B, Anttila V et al. Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population. Nat Genet 2016;48:552‐5. 12. Dudbridge F. Power and predictive accuracy of polygenic risk scores. PLoS Genet 2013;9:e1003348. 13. Wray NR, Lee SH, Mehta D et al. Research review: Polygenic methods and their application to psychiatric traits. J Child Psychol Psychiatry 2014;55:1068‐87. 14. CNV and Schizophrenia Working Groups of the Psychiatric Genomics Consortium. Contribution of copy number variants to schizophrenia from a genome‐wide study of 41,321 subjects. Nat Genet 2017;49:27‐35. 15. Cross‐Disorder Group of the Psychiatric Genomics Consortium . Identification of risk loci with shared effects on five major psychiatric disorders: a genome‐wide analysis. Lancet 2013;381:1371‐9. 16. Lee SH, Ripke S, Neale BM et al. Genetic relationship between five psychiatric disorders estimated from genome‐wide SNPs. Nat Genet 2013;45:984‐94. 17. Uher R. Gene‐environment interactions in common mental disorders: an update and strategy for a genome‐wide search. Soc Psychiatry Psychiatr Epidemiol 2014;49:3‐14. 18. Uher R. Gene‐environment interactions in severe mental illness. Front Psychiatry 2014;5:48. 19. Brown GW, Harris TO. Social origins of depression. A study of psychiatric disorder in women. London: Routledge, 1978. 20. Brown GW, Craig TK, Harris TO. Parental maltreatment and proximal risk factors using the Childhood Experience of Care & Abuse (CECA) instrument: a life‐course study of adult chronic depression ‐ 5. J Affect Disord 2008;110:222‐33. 21. Arseneault L, Cannon M, Fisher HL et al. Childhood trauma and children's emerging psychotic symptoms: a genetically sensitive longitudinal cohort study. Am J Psychiatry 2011;168:65‐72. 22. Davis J, Eyre H, Jacka FN et al. A review of vulnerability and risks for schizophrenia: beyond the two hit hypothesis. Neurosci Biobehav Rev 2016;65:185‐94. 23. Arseneault L. The long‐term impact of bullying victimization on mental health. World Psychiatry 2017;16:27‐8. 24. Rai D, Lewis G, Lundberg M et al. Parental socioeconomic status and risk of offspring autism spectrum disorders in a Swedish population‐based study. J Am Acad Child Adolesc Psychiatry 2012;51:467‐76. 25. Vassos E, Agerbo E, Mors O et al. Urban‐rural differences in incidence rates of psychiatric disorders in Denmark. Br J Psychiatry 2015;208:435‐40. 26. Davis J, Eyre H, Jacka FN et al. A review of vulnerability and risks for schizophrenia: Beyond the two hit hypothesis. Neurosci Biobehav Rev 2016;65:185‐94. 27. Collishaw S, Pickles A, Messer J et al. Resilience to adult psychopathology following childhood maltreatment: evidence from a community sample. Child Abuse Negl 2007;31:211‐29. 28. Cicchetti D. Resilience under conditions of extreme stress: a multilevel perspective. World Psychiatry 2010;9:145‐54. 29. Rutten BP, Hammels C, Geschwind N et al. Resilience in mental health: linking psychological and neurobiological perspectives. Acta Psychiatr Scand 2013;128:3‐20. 30. Starr LR, Hammen C, Conway CC et al. Sensitizing effect of early adversity on depressive reactions to later proximal stress: moderation by polymorphisms in serotonin transporter and corticotropin releasing hormone receptor genes in a 20‐year longitudinal study. Dev Psychopathol 2014;26:1241‐54. 31. Hanscombe KB, Trzaskowski M, Haworth CM et al. Socioeconomic status (SES) and children's intelligence (IQ): in a UK‐representative sample SES moderates the environmental, not genetic, effect on IQ. PLoS One 2012;7:e30320. 32. Padmanabhan JL, Shah JL, Tandon N et al. The “polyenviromic risk score”: aggregating environmental risk factors predicts conversion to psychosis in familial high‐risk subjects. Schizophr Res (in press). 33. Johnson SB, Riis JL, Noble KG. State of the art review: poverty and the developing brain. Pediatrics 2016;137:1‐10. 34. Taylor PJ. The unreliability of high human heritability estimates and small shared effects of growing up in the same family. Biol Theory 2008;2:387‐97. 35. Byrd AL, Manuck SB. MAOA, childhood maltreatment, and antisocial beh * avior: meta‐analysis of a gene‐environment interaction. Biol Psychiatry 2014;75:9‐17. 36. Taylor A, Kim‐Cohen J. Meta‐analysis of gene‐environment interactions in developmental psychopathology. Dev Psychopathol 2007;19:1029‐37. 37. Hosang GM, Shiles C, Tansey KE et al. Interaction between stress and the BDNF Val66Met polymorphism in depression: a systematic review and meta‐analysis. BMC Med 2014;12:7. 38. Karg K, Burmeister M, Shedden K et al. The serotonin transporter promoter variant (5‐HTTLPR), stress, and depression meta‐analysis revisited: evidence of genetic moderation. Arch Gen Psychiatry 2011;68:444‐54. 39. Brown GW, Ban M, Craig TK et al. Serotonin transporter length polymorphism, childhood maltreatment, and chronic depression: a specific gene‐environment interaction. Depress Anxiety 2013;30:5‐13. 40. Uher R, Caspi A, Houts R et al. Serotonin transporter gene moderates childhood maltreatment's effects on persistent but not single‐episode depression: replications and implications for resolving inconsistent results. J Affect Disord 2011;135:56‐65. 41. Zammit S, Spurlock G, Williams H et al. Genotype effects of CHRNA7, CNR1 and COMT in schizophrenia: interactions with tobacco and cannabis use. Br J Psychiatry 2007;191:402‐7. 42. van Winkel R. Family‐based analysis of genetic variation underlying psychosis‐inducing effects of cannabis: sibling analysis and proband follow‐up. Arch Gen Psychiatry 2011;68:148‐57. 43. Di Forti M, Iyegbe C, Sallis H et al. Confirmation that the AKT1 (rs2494732) genotype influences the risk of psychosis in cannabis users. Biol Psychiatry 2012;72:811‐6. 44. Morgan CJ, Freeman TP, Powell J et al. AKT1 genotype moderates the acute psychotomimetic effects of naturalistically smoked cannabis in young cannabis smokers. Transl Psychiatry 2016;6:e738. 45. Borglum AD, Demontis D, Grove J et al. Genome‐wide study of association and interaction with maternal cytomegalovirus infection suggests new schizophrenia loci. Mol Psychiatry 2014;19:325‐33. 46. Dunn EC, Wiste A, Radmanesh F et al. Genome‐wide association study (GWAS) and genome‐wide by environment interaction study (GWEIS) of depressive symptoms in African American and Hispanic/Latina women. Depress Anxiety 2016;33:265‐80. 47. Lee SH, Byrne EM, Hultman CM et al. New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis. Int J Epidemiol 2015;44:1706‐21. 48. Keers R, Coleman JR, Lester KJ et al. A genome‐wide test of the differential susceptibility hypothesis reveals a genetic predictor of differential response to psychological treatments for child anxiety disorders. Psychother Psychosom 2016;85:146‐58. 49. Green EK, Grozeva D, Jones I et al. The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia. Mol Psychiatry 2010;15:1016‐22. 50. Li J, Zhao L, You Y et al. Schizophrenia related variants in CACNA1C also confer risk of autism. PLoS One 2015;10:e0133247. 51. Pasparakis E, Koiliari E, Zouraraki C et al. The effects of the CACNA1C rs1006737 A/G on affective startle modulation in healthy males. Eur Psychiatry 2015;30:492‐8. 52. Uher R, Rutter M. Basing psychiatric classification on scientific foundation: problems and prospects. Int Rev Psychiatry 2012; 24: 591‐605. 53. Stringaris A, Goodman R. Longitudinal outcome of youth oppositionality: irritable, headstrong, and hurtful behaviors have distinctive predictions. J Am Acad Child Adolesc Psychiatry 2009;48:404‐12. 54. Jaddoe VW, van Duijn CM, Franco OH et al. The Generation R Study: design and cohort update 2012. Eur J Epidemiol 2012; 27: 739‐56. 55. Judd LL, Akiskal HS, Maser JD et al. A prospective 12‐year study of subsyndromal and syndromal depressive symptoms in unipolar major depressive disorders. Arch Gen Psychiatry 1998;55:694‐700. 56. Judd LL, Akiskal HS, Schettler PJ et al. The long‐term natural history of the weekly symptomatic status of bipolar I disorder. Arch Gen Psychiatry 2002;59:530‐7. 57. Zanarini MC, Frankenburg FR, Reich DB et al. Attainment and stability of sustained symptomatic remission and recovery among patients with borderline personality disorder and axis II comparison subjects: a 16‐year prospective follow‐up study. Am J Psychiatry 2012;169:476‐83. 58. McGuffin P, Katz R, Watkins S et al. A hospital‐based twin register of the heritability of DSM‐IV unipolar depression. Arch Gen Psychiatry 1996;53:129‐36. 59. Nanni V, Uher R, Danese A. Childhood maltreatment predicts unfavorable course of illness and treatment outcome in depression: a meta‐analysis. Am J Psychiatry 2012;169:141‐51. 60. Maj M. Cycloid psychotic disorder: validation of the concept by means of a follow‐up and a family study. Psychopathology 1990;23:196‐204. 61. Pfuhlmann B, Jabs B, Althaus G et al. Cycloid psychoses are not part of a bipolar affective spectrum: results of a controlled family study. J Affect Disord 2004;83:11‐9. 62. Cade JF. Lithium salts in the treatment of psychotic excitement. Med J Aust 1949;2:349‐52. 63. Iniesta R, Stahl D, McGuffin P. Machine learning, statistical learning and the future of biological research in psychiatry. Psychol Med 2016;46:2455‐65. 64. Han B, Pouget JG, Slowikowski K et al. A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases. Nat Genet 2016;48:803‐10. 65. Uher R. The implications of gene‐environment interactions in depression: will cause inform cure? Mol Psychiatry 2008;13:1070‐8.